| Roanoke to LaGrange (Georgia) | 410.52 mi (660.67 km) |
| Roanoke to Laguna Beach (California) | 2,130.15 mi (3,428.14 km) |
| Roanoke to Laguna Hills (California) | 2,125.76 mi (3,421.08 km) |
| Roanoke to Laguna Niguel (California) | 2,127.44 mi (3,423.79 km) |
| Roanoke to Laguna Woods (California) | 2,127.06 mi (3,423.18 km) |
| Roanoke to Lahaina (Hawaii) | 4,645.71 mi (7,476.55 km) |
| Roanoke to Lake Arbor (Maryland) | 204.04 mi (328.37 km) |
| Roanoke to Lake Barcroft (Virginia) | 187.10 mi (301.11 km) |
| Roanoke to Lake Butler (Florida) | 614.41 mi (988.79 km) |
| Roanoke to Lake Charles (Louisiana) | 903.56 mi (1,454.14 km) |
| Roanoke to Lake City (Florida) | 513.48 mi (826.37 km) |
| Roanoke to Lake Elmo (Minnesota) | 857.25 mi (1,379.62 km) |
| Roanoke to Lake Elsinore (California) | 2,103.82 mi (3,385.77 km) |
| Roanoke to Lake Forest (California) | 2,122.79 mi (3,416.30 km) |
| Roanoke to Lake Forest (Illinois) | 541.40 mi (871.29 km) |
