| Roanoke to Friendly (Maryland) | 192.43 mi (309.69 km) |
| Roanoke to Friendswood (Texas) | 1,028.00 mi (1,654.41 km) |
| Roanoke to Frisco (Texas) | 992.01 mi (1,596.48 km) |
| Roanoke to Front Royal (Virginia) | 149.20 mi (240.12 km) |
| Roanoke to Fruit Cove (Florida) | 505.24 mi (813.11 km) |
| Roanoke to Fruita (Colorado) | 1,560.73 mi (2,511.75 km) |
| Roanoke to Fruitville (Florida) | 702.48 mi (1,130.53 km) |
| Roanoke to Fuller Heights (Florida) | 657.18 mi (1,057.63 km) |
| Roanoke to Fullerton (California) | 2,132.19 mi (3,431.42 km) |
| Roanoke to Fullerton (Pennsylvania) | 333.76 mi (537.13 km) |
| Roanoke to Fulshear (Texas) | 1,054.53 mi (1,697.11 km) |
| Roanoke to Fulton (Missouri) | 660.90 mi (1,063.62 km) |
| Roanoke to Fulton (New York) | 456.95 mi (735.38 km) |
| Roanoke to Fuquay-Varina (North Carolina) | 133.52 mi (214.89 km) |
| Roanoke to Gadsden (Alabama) | 408.19 mi (656.91 km) |
