| Roanoke to Eugene (Oregon) | 2,282.74 mi (3,673.72 km) |
| Roanoke to Euless (Texas) | 1,013.76 mi (1,631.50 km) |
| Roanoke to Eureka (California) | 2,359.34 mi (3,796.98 km) |
| Roanoke to Eureka (Missouri) | 588.70 mi (947.41 km) |
| Roanoke to Eustis (Florida) | 590.33 mi (950.05 km) |
| Roanoke to Evans (Colorado) | 1,346.36 mi (2,166.76 km) |
| Roanoke to Evans (Georgia) | 284.52 mi (457.90 km) |
| Roanoke to Evanston (Illinois) | 526.72 mi (847.68 km) |
| Roanoke to Evanston (Wyoming) | 1,672.09 mi (2,690.97 km) |
| Roanoke to Evansville (Indiana) | 417.31 mi (671.59 km) |
| Roanoke to Everett (Massachusetts) | 589.91 mi (949.37 km) |
| Roanoke to Everett (Washington) | 2,237.26 mi (3,600.53 km) |
| Roanoke to Evergreen Park (Illinois) | 514.09 mi (827.35 km) |
| Roanoke to Ewa Beach (Hawaii) | 4,702.26 mi (7,567.56 km) |
| Roanoke to Ewa Gentry (Hawaii) | 4,702.67 mi (7,568.22 km) |
