| Roanoke to Elkhart (Indiana) | 441.94 mi (711.23 km) |
| Roanoke to Elkhorn (Wisconsin) | 587.00 mi (944.68 km) |
| Roanoke to Elko (Nevada) | 1,923.41 mi (3,095.43 km) |
| Roanoke to Elkridge (Maryland) | 218.99 mi (352.43 km) |
| Roanoke to Elkton (Maryland) | 275.63 mi (443.59 km) |
| Roanoke to Ellensburg (Washington) | 2,157.96 mi (3,472.90 km) |
| Roanoke to Ellicott City (Maryland) | 218.56 mi (351.73 km) |
| Roanoke to Elmhurst (Illinois) | 531.23 mi (854.93 km) |
| Roanoke to Elmira (New York) | 372.37 mi (599.28 km) |
| Roanoke to Elmont (New York) | 410.51 mi (660.65 km) |
| Roanoke to Elmwood Park (Illinois) | 526.85 mi (847.88 km) |
| Roanoke to Elmwood Park (New Jersey) | 400.82 mi (645.07 km) |
| Roanoke to Elon (North Carolina) | 85.04 mi (136.86 km) |
| Roanoke to Eloy (Arizona) | 1,809.04 mi (2,911.37 km) |
| Roanoke to Elwood (New York) | 432.08 mi (695.36 km) |
