| Roanoke to Eagan (Minnesota) | 861.19 mi (1,385.96 km) |
| Roanoke to Eagle (Idaho) | 1,948.32 mi (3,135.52 km) |
| Roanoke to Eagle Mountain (Utah) | 1,729.24 mi (2,782.95 km) |
| Roanoke to Eagle Pass (Texas) | 1,324.62 mi (2,131.76 km) |
| Roanoke to Easley (South Carolina) | 224.43 mi (361.19 km) |
| Roanoke to East Bakersfield (California) | 2,160.29 mi (3,476.65 km) |
| Roanoke to East Bethel (Minnesota) | 883.41 mi (1,421.71 km) |
| Roanoke to East Chicago (Indiana) | 500.67 mi (805.76 km) |
| Roanoke to East Cleveland (Ohio) | 306.33 mi (492.99 km) |
| Roanoke to East Glenville (New York) | 500.42 mi (805.35 km) |
| Roanoke to East Grand Rapids (Michigan) | 492.20 mi (792.12 km) |
| Roanoke to East Hemet (California) | 2,081.31 mi (3,349.55 km) |
| Roanoke to East Highland Park (Virginia) | 142.59 mi (229.48 km) |
| Roanoke to East Honolulu (Hawaii) | 4,687.57 mi (7,543.92 km) |
| Roanoke to East Islip (New York) | 434.44 mi (699.16 km) |
