| Roanoke to Duluth (Minnesota) | 904.27 mi (1,455.28 km) |
| Roanoke to Dumas (Texas) | 1,222.30 mi (1,967.10 km) |
| Roanoke to Dumont (New Jersey) | 407.84 mi (656.36 km) |
| Roanoke to Duncan (Oklahoma) | 1,021.26 mi (1,643.56 km) |
| Roanoke to Duncanville (Texas) | 1,010.28 mi (1,625.88 km) |
| Roanoke to Dundalk (Maryland) | 232.87 mi (374.77 km) |
| Roanoke to Dunedin (Florida) | 659.55 mi (1,061.45 km) |
| Roanoke to Dunkirk (New York) | 360.92 mi (580.85 km) |
| Roanoke to Dunmore (Pennsylvania) | 368.31 mi (592.74 km) |
| Roanoke to Dunwoody (Georgia) | 336.03 mi (540.79 km) |
| Roanoke to Durango (Colorado) | 1,529.45 mi (2,461.42 km) |
| Roanoke to Durant (Oklahoma) | 948.96 mi (1,527.21 km) |
| Roanoke to Durham (North Carolina) | 107.18 mi (172.48 km) |
| Roanoke to Dyer (Indiana) | 497.24 mi (800.23 km) |
| Roanoke to Dyersburg (Tennessee) | 528.74 mi (850.92 km) |
