| Roanoke to Crawfordsville (Indiana) | 420.13 mi (676.13 km) |
| Roanoke to Crest Hill (Illinois) | 526.33 mi (847.04 km) |
| Roanoke to Crestview (Florida) | 589.03 mi (947.96 km) |
| Roanoke to Crestwood (Illinois) | 512.82 mi (825.30 km) |
| Roanoke to Crestwood (Missouri) | 574.48 mi (924.53 km) |
| Roanoke to Creve Coeur (Missouri) | 578.70 mi (931.33 km) |
| Roanoke to Crofton (Maryland) | 214.72 mi (345.55 km) |
| Roanoke to Crossville (Tennessee) | 295.75 mi (475.96 km) |
| Roanoke to Crowley (Louisiana) | 863.01 mi (1,388.88 km) |
| Roanoke to Crowley (Texas) | 1,035.98 mi (1,667.25 km) |
| Roanoke to Crown Point (Indiana) | 487.01 mi (783.77 km) |
| Roanoke to Crystal (Minnesota) | 877.52 mi (1,412.23 km) |
| Roanoke to Crystal Lake (Illinois) | 560.95 mi (902.77 km) |
| Roanoke to Cudahy (California) | 2,144.52 mi (3,451.28 km) |
| Roanoke to Cudahy (Wisconsin) | 572.14 mi (920.77 km) |
