| Roanoke to Cordele (Georgia) | 426.73 mi (686.76 km) |
| Roanoke to Corinth (Mississippi) | 503.79 mi (810.77 km) |
| Roanoke to Corinth (Texas) | 1,005.61 mi (1,618.37 km) |
| Roanoke to Cornelius (North Carolina) | 134.94 mi (217.17 km) |
| Roanoke to Cornelius (Oregon) | 2,275.64 mi (3,662.29 km) |
| Roanoke to Corning (New York) | 370.00 mi (595.45 km) |
| Roanoke to Corona (California) | 2,112.78 mi (3,400.18 km) |
| Roanoke to Coronado (California) | 2,116.54 mi (3,406.24 km) |
| Roanoke to Corpus Christi (Texas) | 1,207.60 mi (1,943.45 km) |
| Roanoke to Corsicana (Texas) | 1,002.62 mi (1,613.55 km) |
| Roanoke to Cortland (New York) | 418.58 mi (673.63 km) |
| Roanoke to Corvallis (Oregon) | 2,288.82 mi (3,683.50 km) |
| Roanoke to Coshocton (Ohio) | 229.88 mi (369.96 km) |
| Roanoke to Costa Mesa (California) | 2,135.93 mi (3,437.44 km) |
| Roanoke to Coto de Caza (California) | 2,119.47 mi (3,410.96 km) |
