| Roanoke to Conyers (Georgia) | 337.55 mi (543.23 km) |
| Roanoke to Cookeville (Tennessee) | 317.26 mi (510.58 km) |
| Roanoke to Coolidge (Arizona) | 1,800.79 mi (2,898.09 km) |
| Roanoke to Coon Rapids (Minnesota) | 880.69 mi (1,417.33 km) |
| Roanoke to Cooper City (Florida) | 776.31 mi (1,249.35 km) |
| Roanoke to Coos Bay (Oregon) | 2,341.72 mi (3,768.64 km) |
| Roanoke to Copiague (New York) | 423.27 mi (681.19 km) |
| Roanoke to Coppell (Texas) | 1,006.00 mi (1,618.99 km) |
| Roanoke to Copperas Cove (Texas) | 1,108.54 mi (1,784.02 km) |
| Roanoke to Coral Gables (Florida) | 799.95 mi (1,287.40 km) |
| Roanoke to Coral Springs (Florida) | 760.80 mi (1,224.40 km) |
| Roanoke to Coral Terrace (Florida) | 797.05 mi (1,282.73 km) |
| Roanoke to Coralville (Iowa) | 690.88 mi (1,111.86 km) |
| Roanoke to Coram (New York) | 448.11 mi (721.16 km) |
| Roanoke to Corcoran (California) | 2,179.86 mi (3,508.14 km) |
