| Roanoke to Commerce (California) | 2,142.14 mi (3,447.45 km) |
| Roanoke to Commerce City (Colorado) | 1,351.64 mi (2,175.26 km) |
| Roanoke to Compton (California) | 2,148.40 mi (3,457.51 km) |
| Roanoke to Comstock Park (Michigan) | 499.62 mi (804.06 km) |
| Roanoke to Concord (California) | 2,281.37 mi (3,671.51 km) |
| Roanoke to Concord (Missouri) | 573.06 mi (922.25 km) |
| Roanoke to Concord (New Hampshire) | 603.78 mi (971.69 km) |
| Roanoke to Concord (North Carolina) | 135.62 mi (218.26 km) |
| Roanoke to Conneaut (Ohio) | 322.85 mi (519.58 km) |
| Roanoke to Connersville (Indiana) | 324.95 mi (522.96 km) |
| Roanoke to Conroe (Texas) | 1,010.72 mi (1,626.60 km) |
| Roanoke to Converse (Texas) | 1,183.99 mi (1,905.46 km) |
| Roanoke to Conway (Arkansas) | 713.60 mi (1,148.43 km) |
| Roanoke to Conway (Florida) | 611.94 mi (984.83 km) |
| Roanoke to Conway (South Carolina) | 243.07 mi (391.18 km) |
