| Roanoke to Cold Springs (Nevada) | 2,152.89 mi (3,464.74 km) |
| Roanoke to Coldwater (Michigan) | 419.37 mi (674.92 km) |
| Roanoke to Colesville (Maryland) | 202.89 mi (326.51 km) |
| Roanoke to College (Alaska) | 3,281.40 mi (5,280.90 km) |
| Roanoke to College Park (Georgia) | 357.17 mi (574.81 km) |
| Roanoke to College Park (Maryland) | 202.70 mi (326.22 km) |
| Roanoke to College Station (Texas) | 1,042.53 mi (1,677.79 km) |
| Roanoke to Collegedale (Tennessee) | 322.86 mi (519.60 km) |
| Roanoke to Colleyville (Texas) | 1,016.39 mi (1,635.72 km) |
| Roanoke to Collierville (Tennessee) | 564.50 mi (908.47 km) |
| Roanoke to Collinsville (Illinois) | 555.42 mi (893.86 km) |
| Roanoke to Colonia (New Jersey) | 379.89 mi (611.37 km) |
| Roanoke to Colonial Heights (Virginia) | 140.82 mi (226.63 km) |
| Roanoke to Colonial Park (Pennsylvania) | 268.93 mi (432.80 km) |
| Roanoke to Colorado Springs (Colorado) | 1,349.35 mi (2,171.58 km) |
