| Roanoke to Clemson (South Carolina) | 239.99 mi (386.23 km) |
| Roanoke to Clermont (Florida) | 612.84 mi (986.27 km) |
| Roanoke to Cleveland (Mississippi) | 652.62 mi (1,050.29 km) |
| Roanoke to Cleveland (Ohio) | 304.27 mi (489.67 km) |
| Roanoke to Cleveland (Tennessee) | 309.70 mi (498.42 km) |
| Roanoke to Cleveland Heights (Ohio) | 304.75 mi (490.44 km) |
| Roanoke to Cliffside Park (New Jersey) | 403.03 mi (648.62 km) |
| Roanoke to Clifton (Colorado) | 1,546.72 mi (2,489.20 km) |
| Roanoke to Clifton (New Jersey) | 397.53 mi (639.76 km) |
| Roanoke to Clinton (Iowa) | 631.43 mi (1,016.19 km) |
| Roanoke to Clinton (Maryland) | 194.75 mi (313.42 km) |
| Roanoke to Clinton (Mississippi) | 679.54 mi (1,093.61 km) |
| Roanoke to Clinton (Utah) | 1,729.50 mi (2,783.36 km) |
| Roanoke to Clive (Iowa) | 795.72 mi (1,280.59 km) |
| Roanoke to Cloquet (Minnesota) | 914.32 mi (1,471.45 km) |
