| Roanoke to Carrollwood (Florida) | 654.14 mi (1,052.73 km) |
| Roanoke to Carson (California) | 2,151.11 mi (3,461.88 km) |
| Roanoke to Carson City (Nevada) | 2,146.58 mi (3,454.58 km) |
| Roanoke to Carteret (New Jersey) | 383.30 mi (616.86 km) |
| Roanoke to Cartersville (Georgia) | 346.45 mi (557.56 km) |
| Roanoke to Carthage (Missouri) | 789.68 mi (1,270.87 km) |
| Roanoke to Cary (Illinois) | 556.55 mi (895.68 km) |
| Roanoke to Cary (North Carolina) | 121.19 mi (195.04 km) |
| Roanoke to Casa de Oro-Mount Helix (California) | 2,103.77 mi (3,385.69 km) |
| Roanoke to Casa Grande (Arizona) | 1,814.46 mi (2,920.10 km) |
| Roanoke to Casas Adobes (Arizona) | 1,785.97 mi (2,874.24 km) |
| Roanoke to Cascades (Virginia) | 185.52 mi (298.57 km) |
| Roanoke to Casper (Wyoming) | 1,439.51 mi (2,316.67 km) |
| Roanoke to Casselberry (Florida) | 600.52 mi (966.44 km) |
| Roanoke to Castaic (California) | 2,158.63 mi (3,473.97 km) |
