| Roanoke to Cadillac (Michigan) | 559.65 mi (900.68 km) |
| Roanoke to Caguas (Puerto Rico) | 1,563.04 mi (2,515.48 km) |
| Roanoke to Cahokia (Illinois) | 563.84 mi (907.41 km) |
| Roanoke to Calabasas (California) | 2,167.54 mi (3,488.32 km) |
| Roanoke to Caldwell (Idaho) | 1,961.91 mi (3,157.40 km) |
| Roanoke to Caledonia (Wisconsin) | 566.01 mi (910.91 km) |
| Roanoke to Calera (Alabama) | 478.48 mi (770.04 km) |
| Roanoke to Calexico (California) | 2,024.56 mi (3,258.21 km) |
| Roanoke to Calhoun (Georgia) | 338.78 mi (545.21 km) |
| Roanoke to California (Maryland) | 201.75 mi (324.69 km) |
| Roanoke to California City (California) | 2,104.39 mi (3,386.69 km) |
| Roanoke to Callaway (Florida) | 588.93 mi (947.78 km) |
| Roanoke to Calumet City (Illinois) | 503.46 mi (810.25 km) |
| Roanoke to Calverton (Maryland) | 204.52 mi (329.14 km) |
| Roanoke to Camano (Washington) | 2,252.25 mi (3,624.65 km) |
