| Roanoke to Anoka (Minnesota) | 885.24 mi (1,424.66 km) |
| Roanoke to Ansonia (Connecticut) | 462.94 mi (745.03 km) |
| Roanoke to Antelope (California) | 2,237.21 mi (3,600.43 km) |
| Roanoke to Anthem (Arizona) | 1,814.02 mi (2,919.38 km) |
| Roanoke to Antioch (California) | 2,270.32 mi (3,653.73 km) |
| Roanoke to Antioch (Illinois) | 559.87 mi (901.03 km) |
| Roanoke to Apache Junction (Arizona) | 1,791.40 mi (2,882.97 km) |
| Roanoke to Apex (North Carolina) | 123.14 mi (198.17 km) |
| Roanoke to Apollo Beach (Florida) | 672.68 mi (1,082.57 km) |
| Roanoke to Apopka (Florida) | 599.56 mi (964.90 km) |
| Roanoke to Apple Valley (California) | 2,079.97 mi (3,347.39 km) |
| Roanoke to Apple Valley (Minnesota) | 860.07 mi (1,384.14 km) |
| Roanoke to Appleton (Wisconsin) | 653.87 mi (1,052.29 km) |
| Roanoke to Arbutus (Maryland) | 223.16 mi (359.14 km) |
| Roanoke to Arcadia (California) | 2,133.07 mi (3,432.85 km) |
