| Roanoke to Altus (Oklahoma) | 1,095.01 mi (1,762.25 km) |
| Roanoke to Alum Rock (California) | 2,280.88 mi (3,670.72 km) |
| Roanoke to Alvin (Texas) | 1,037.66 mi (1,669.95 km) |
| Roanoke to Amarillo (Texas) | 1,224.65 mi (1,970.88 km) |
| Roanoke to Amelia (Ohio) | 261.22 mi (420.40 km) |
| Roanoke to American Canyon (California) | 2,292.06 mi (3,688.71 km) |
| Roanoke to American Fork (Utah) | 1,717.62 mi (2,764.25 km) |
| Roanoke to Americus (Georgia) | 433.59 mi (697.79 km) |
| Roanoke to Ames (Iowa) | 796.22 mi (1,281.39 km) |
| Roanoke to Amherst (Ohio) | 309.68 mi (498.38 km) |
| Roanoke to Ammon (Idaho) | 1,726.24 mi (2,778.11 km) |
| Roanoke to Amsterdam (New York) | 495.72 mi (797.79 km) |
| Roanoke to Anacortes (Washington) | 2,260.86 mi (3,638.50 km) |
| Roanoke to Anaheim (California) | 2,129.26 mi (3,426.71 km) |
| Roanoke to Anchorage (Alaska) | 3,326.95 mi (5,354.21 km) |
