| Roanoke to Sesena | 3,984.94 mi (6,413.14 km) |
| Roanoke to Sestao | 3,931.00 mi (6,326.34 km) |
| Roanoke to Sevilla | 3,953.20 mi (6,362.07 km) |
| Roanoke to Sevilla La Nueva | 3,962.20 mi (6,376.55 km) |
| Roanoke to Silla | 4,165.02 mi (6,702.96 km) |
| Roanoke to Silleda | 3,699.91 mi (5,954.43 km) |
| Roanoke to Sitges | 4,213.97 mi (6,781.74 km) |
| Roanoke to Socuellamos | 4,051.76 mi (6,520.67 km) |
| Roanoke to Soller | 4,301.14 mi (6,922.02 km) |
| Roanoke to Solsona | 4,177.99 mi (6,723.82 km) |
| Roanoke to Son Servera | 4,336.97 mi (6,979.68 km) |
| Roanoke to Sonseca | 3,984.03 mi (6,411.68 km) |
| Roanoke to Sopelana | 3,930.38 mi (6,325.34 km) |
| Roanoke to Soria | 3,997.74 mi (6,433.74 km) |
| Roanoke to Suances | 3,879.19 mi (6,242.96 km) |
