| Roanoke to Santa Ursula | 3,666.38 mi (5,900.48 km) |
| Roanoke to Santander | 3,889.86 mi (6,260.12 km) |
| Roanoke to Santany | 4,334.43 mi (6,975.60 km) |
| Roanoke to Santiago de Compostela | 3,680.90 mi (5,923.83 km) |
| Roanoke to Santiago del Teide | 3,652.98 mi (5,878.91 km) |
| Roanoke to Santiponce | 3,944.95 mi (6,348.78 km) |
| Roanoke to Santomera | 4,173.28 mi (6,716.25 km) |
| Roanoke to Santona | 3,906.58 mi (6,287.04 km) |
| Roanoke to Santurce-Antiguo | 3,929.29 mi (6,323.59 km) |
| Roanoke to Sarria | 3,736.80 mi (6,013.80 km) |
| Roanoke to Sauzal | 3,667.70 mi (5,902.59 km) |
| Roanoke to Sedavi | 4,164.29 mi (6,701.78 km) |
| Roanoke to Segorbe | 4,146.60 mi (6,673.31 km) |
| Roanoke to Segovia | 3,941.44 mi (6,343.13 km) |
| Roanoke to Senmanat | 4,218.19 mi (6,788.52 km) |
