| Roanoke to Ede | 4,076.93 mi (6,561.19 km) |
| Roanoke to Eemnes | 4,055.37 mi (6,526.49 km) |
| Roanoke to Eerbeek | 4,091.05 mi (6,583.91 km) |
| Roanoke to Eersel | 4,081.45 mi (6,568.46 km) |
| Roanoke to Eijsden | 4,112.39 mi (6,618.25 km) |
| Roanoke to Eindhoven | 4,085.89 mi (6,575.60 km) |
| Roanoke to Elburg | 4,073.67 mi (6,555.94 km) |
| Roanoke to Emmeloord | 4,063.07 mi (6,538.89 km) |
| Roanoke to Emmen | 4,105.62 mi (6,607.35 km) |
| Roanoke to Enkhuizen | 4,045.80 mi (6,511.08 km) |
| Roanoke to Enschede | 4,120.79 mi (6,631.77 km) |
| Roanoke to Epe | 4,081.48 mi (6,568.51 km) |
| Roanoke to Ermelo | 4,068.45 mi (6,547.54 km) |
| Roanoke to Etten-Leur | 4,048.55 mi (6,515.52 km) |
| Roanoke to Franeker | 4,042.12 mi (6,505.17 km) |
