| Roanoke to Spello | 4,648.36 mi (7,480.82 km) |
| Roanoke to Spilamberto | 4,523.69 mi (7,280.18 km) |
| Roanoke to Spilimbergo | 4,549.11 mi (7,321.09 km) |
| Roanoke to Spinea | 4,540.20 mi (7,306.75 km) |
| Roanoke to Spoleto | 4,657.10 mi (7,494.88 km) |
| Roanoke to Spoltore | 4,731.22 mi (7,614.17 km) |
| Roanoke to Spresiano | 4,534.18 mi (7,297.06 km) |
| Roanoke to Squinzano | 4,977.07 mi (8,009.82 km) |
| Roanoke to Statte | 4,934.84 mi (7,941.86 km) |
| Roanoke to Stezzano | 4,428.44 mi (7,126.89 km) |
| Roanoke to Strada | 4,568.79 mi (7,352.75 km) |
| Roanoke to Stradella | 4,431.60 mi (7,131.97 km) |
| Roanoke to Striano | 4,809.63 mi (7,740.36 km) |
| Roanoke to Subiaco | 4,704.42 mi (7,571.04 km) |
| Roanoke to Sulmona | 4,736.57 mi (7,622.78 km) |
