| Roanoke to Sestu | 4,615.88 mi (7,428.54 km) |
| Roanoke to Settimo Torinese | 4,363.64 mi (7,022.60 km) |
| Roanoke to Seveso | 4,406.63 mi (7,091.78 km) |
| Roanoke to Sezze | 4,718.44 mi (7,593.59 km) |
| Roanoke to Siano | 4,815.81 mi (7,750.29 km) |
| Roanoke to Siena | 4,578.47 mi (7,368.34 km) |
| Roanoke to Signa | 4,552.56 mi (7,326.64 km) |
| Roanoke to Silea | 4,540.49 mi (7,307.21 km) |
| Roanoke to Silvi Paese | 4,726.79 mi (7,607.04 km) |
| Roanoke to Sinalunga | 4,599.51 mi (7,402.19 km) |
| Roanoke to Siniscola | 4,599.64 mi (7,402.40 km) |
| Roanoke to Sinnai | 4,620.92 mi (7,436.65 km) |
| Roanoke to Siracusa | 4,982.90 mi (8,019.20 km) |
| Roanoke to Solaro | 4,405.24 mi (7,089.55 km) |
| Roanoke to Soliera | 4,512.87 mi (7,262.77 km) |
