| Roanoke to Santa Venerina | 4,952.41 mi (7,970.13 km) |
| Roanoke to Santeramo in Colle | 4,907.02 mi (7,897.08 km) |
| Roanoke to Santo Stefano di Magra | 4,488.33 mi (7,223.27 km) |
| Roanoke to Santo Stino di Livenza | 4,554.08 mi (7,329.09 km) |
| Roanoke to Sarezzo | 4,451.81 mi (7,164.50 km) |
| Roanoke to Sarno | 4,811.85 mi (7,743.92 km) |
| Roanoke to Saronno | 4,402.90 mi (7,085.78 km) |
| Roanoke to Sarzana | 4,491.90 mi (7,229.01 km) |
| Roanoke to Sassari | 4,542.59 mi (7,310.60 km) |
| Roanoke to Sasso Marconi | 4,538.22 mi (7,303.56 km) |
| Roanoke to Sassuolo | 4,513.12 mi (7,263.16 km) |
| Roanoke to Sava | 4,957.26 mi (7,977.93 km) |
| Roanoke to Saviano | 4,803.74 mi (7,730.88 km) |
| Roanoke to Savigliano | 4,373.01 mi (7,037.69 km) |
| Roanoke to Savignano sul Panaro | 4,526.08 mi (7,284.02 km) |
