| Roanoke to Sacile | 4,538.49 mi (7,303.99 km) |
| Roanoke to Sala Consilina | 4,870.81 mi (7,838.82 km) |
| Roanoke to Salemi | 4,840.31 mi (7,789.72 km) |
| Roanoke to Salerno | 4,823.20 mi (7,762.19 km) |
| Roanoke to Salo | 4,467.64 mi (7,189.97 km) |
| Roanoke to Salsomaggiore Terme | 4,469.65 mi (7,193.21 km) |
| Roanoke to Saluzzo | 4,366.92 mi (7,027.87 km) |
| Roanoke to Salzano | 4,536.99 mi (7,301.58 km) |
| Roanoke to Samarate | 4,392.29 mi (7,068.71 km) |
| Roanoke to San Benedetto del Tronto | 4,702.32 mi (7,567.66 km) |
| Roanoke to San Biagio di Callalta | 4,542.98 mi (7,311.21 km) |
| Roanoke to San Bonifacio | 4,506.15 mi (7,251.94 km) |
| Roanoke to San Casciano in Val di Pesa | 4,560.58 mi (7,339.55 km) |
| Roanoke to San Cataldo | 4,907.25 mi (7,897.46 km) |
| Roanoke to San Cesareo | 4,695.35 mi (7,556.44 km) |
