| Roanoke to Orbetello | 4,603.42 mi (7,408.49 km) |
| Roanoke to Oria | 4,956.33 mi (7,976.44 km) |
| Roanoke to Oristano | 4,571.94 mi (7,357.83 km) |
| Roanoke to Orta Nova | 4,840.94 mi (7,790.74 km) |
| Roanoke to Orte | 4,654.39 mi (7,490.52 km) |
| Roanoke to Ortona | 4,746.33 mi (7,638.48 km) |
| Roanoke to Orvieto | 4,633.27 mi (7,456.52 km) |
| Roanoke to Orzinuovi | 4,448.55 mi (7,159.26 km) |
| Roanoke to Osimo | 4,666.11 mi (7,509.37 km) |
| Roanoke to Ospitaletto | 4,449.49 mi (7,160.76 km) |
| Roanoke to Ostuni | 4,945.18 mi (7,958.50 km) |
| Roanoke to Ottaviano | 4,804.46 mi (7,732.03 km) |
| Roanoke to Ovada | 4,417.57 mi (7,109.39 km) |
| Roanoke to Ozieri | 4,567.68 mi (7,350.97 km) |
| Roanoke to Paceco | 4,822.64 mi (7,761.29 km) |
