| Rio Grande City to Worthington (Ohio) | 1,311.83 mi (2,111.19 km) |
| Rio Grande City to Wright (Florida) | 791.06 mi (1,273.08 km) |
| Rio Grande City to Wyandanch (New York) | 1,759.74 mi (2,832.02 km) |
| Rio Grande City to Wyandotte (Michigan) | 1,407.88 mi (2,265.76 km) |
| Rio Grande City to Wylie (Texas) | 480.16 mi (772.74 km) |
| Rio Grande City to Wyndham (Virginia) | 1,462.21 mi (2,353.20 km) |
| Rio Grande City to Wyoming (Michigan) | 1,359.02 mi (2,187.14 km) |
| Rio Grande City to Wyomissing (Pennsylvania) | 1,625.24 mi (2,615.57 km) |
| Rio Grande City to Xenia (Ohio) | 1,256.51 mi (2,022.16 km) |
| Rio Grande City to Yakima (Washington) | 1,833.19 mi (2,950.23 km) |
| Rio Grande City to Yankton (South Dakota) | 1,143.52 mi (1,840.32 km) |
| Rio Grande City to Yauco (Puerto Rico) | 2,117.82 mi (3,408.30 km) |
| Rio Grande City to Yazoo City (Mississippi) | 674.74 mi (1,085.90 km) |
| Rio Grande City to Yeadon (Pennsylvania) | 1,645.46 mi (2,648.10 km) |
| Rio Grande City to Yelm (Washington) | 1,923.39 mi (3,095.40 km) |
