| Rio Grande City to Spout Springs (North Carolina) | 1,321.56 mi (2,126.85 km) |
| Rio Grande City to Spring (Texas) | 329.33 mi (530.01 km) |
| Rio Grande City to Spring Creek (Nevada) | 1,380.05 mi (2,220.97 km) |
| Rio Grande City to Spring Hill (Florida) | 1,008.74 mi (1,623.41 km) |
| Rio Grande City to Spring Hill (Tennessee) | 955.29 mi (1,537.40 km) |
| Rio Grande City to Spring Lake (North Carolina) | 1,321.20 mi (2,126.27 km) |
| Rio Grande City to Spring Valley (California) | 1,174.03 mi (1,889.42 km) |
| Rio Grande City to Spring Valley (Nevada) | 1,177.92 mi (1,895.67 km) |
| Rio Grande City to Spring Valley (New York) | 1,739.49 mi (2,799.44 km) |
| Rio Grande City to Springboro (Ohio) | 1,239.34 mi (1,994.53 km) |
| Rio Grande City to Springdale (Arkansas) | 731.30 mi (1,176.91 km) |
| Rio Grande City to Springdale (New Jersey) | 1,656.91 mi (2,666.54 km) |
| Rio Grande City to Springdale (Ohio) | 1,217.19 mi (1,958.88 km) |
| Rio Grande City to Springfield (Illinois) | 1,065.15 mi (1,714.19 km) |
| Rio Grande City to Springfield (Massachusetts) | 1,840.74 mi (2,962.38 km) |
