| Rio Grande City to South Fulton (Georgia) | 986.88 mi (1,588.23 km) |
| Rio Grande City to South Gate (California) | 1,266.91 mi (2,038.89 km) |
| Rio Grande City to South Hill (Washington) | 1,918.97 mi (3,088.28 km) |
| Rio Grande City to South Holland (Illinois) | 1,229.77 mi (1,979.13 km) |
| Rio Grande City to South Houston (Texas) | 315.23 mi (507.31 km) |
| Rio Grande City to South Huntington (New York) | 1,760.64 mi (2,833.47 km) |
| Rio Grande City to South Jordan (Utah) | 1,235.66 mi (1,988.60 km) |
| Rio Grande City to South Lake Tahoe (California) | 1,499.81 mi (2,413.71 km) |
| Rio Grande City to South Laurel (Maryland) | 1,542.23 mi (2,481.99 km) |
| Rio Grande City to South Lyon (Michigan) | 1,403.08 mi (2,258.04 km) |
| Rio Grande City to South Miami (Florida) | 1,150.02 mi (1,850.77 km) |
| Rio Grande City to South Miami Heights (Florida) | 1,145.33 mi (1,843.23 km) |
| Rio Grande City to South Milwaukee (Wisconsin) | 1,298.33 mi (2,089.46 km) |
| Rio Grande City to South Ogden (Utah) | 1,267.04 mi (2,039.11 km) |
| Rio Grande City to South Pasadena (California) | 1,268.81 mi (2,041.95 km) |
