| Rio Grande City to Oakleaf Plantation (Florida) | 1,065.15 mi (1,714.19 km) |
| Rio Grande City to Oakley (California) | 1,553.20 mi (2,499.64 km) |
| Rio Grande City to Oakton (Virginia) | 1,515.05 mi (2,438.23 km) |
| Rio Grande City to Oakville (Missouri) | 968.97 mi (1,559.41 km) |
| Rio Grande City to Oatfield (Oregon) | 1,857.02 mi (2,988.59 km) |
| Rio Grande City to Ocala (Florida) | 1,036.28 mi (1,667.72 km) |
| Rio Grande City to Ocean Acres (New Jersey) | 1,685.71 mi (2,712.89 km) |
| Rio Grande City to Ocean City (New Jersey) | 1,656.12 mi (2,665.27 km) |
| Rio Grande City to Ocean Pines (Maryland) | 1,603.90 mi (2,581.23 km) |
| Rio Grande City to Ocean Pointe (Hawaii) | 3,726.27 mi (5,996.85 km) |
| Rio Grande City to Ocean Springs (Mississippi) | 670.06 mi (1,078.36 km) |
| Rio Grande City to Oceanside (California) | 1,202.73 mi (1,935.60 km) |
| Rio Grande City to Oceanside (New York) | 1,743.33 mi (2,805.62 km) |
| Rio Grande City to Ocoee (Florida) | 1,069.59 mi (1,721.35 km) |
| Rio Grande City to Oconomowoc (Wisconsin) | 1,293.01 mi (2,080.89 km) |
