| Rio Grande City to Los Alamitos (California) | 1,256.34 mi (2,021.89 km) |
| Rio Grande City to Los Alamos (New Mexico) | 791.07 mi (1,273.11 km) |
| Rio Grande City to Los Altos (California) | 1,556.18 mi (2,504.44 km) |
| Rio Grande City to Los Angeles (California) | 1,282.35 mi (2,063.74 km) |
| Rio Grande City to Los Banos (California) | 1,484.33 mi (2,388.79 km) |
| Rio Grande City to Los Gatos (California) | 1,545.42 mi (2,487.11 km) |
| Rio Grande City to Los Lunas (New Mexico) | 749.96 mi (1,206.94 km) |
| Rio Grande City to Los Osos (California) | 1,439.18 mi (2,316.14 km) |
| Rio Grande City to Loudoun Valley Estates (Virginia) | 1,508.36 mi (2,427.46 km) |
| Rio Grande City to Louisville (Colorado) | 1,006.94 mi (1,620.51 km) |
| Rio Grande City to Louisville (Kentucky) | 1,118.01 mi (1,799.26 km) |
| Rio Grande City to Lovejoy (Georgia) | 994.82 mi (1,601.01 km) |
| Rio Grande City to Loveland (Colorado) | 1,033.70 mi (1,663.57 km) |
| Rio Grande City to Loveland (Ohio) | 1,224.09 mi (1,969.98 km) |
| Rio Grande City to Loves Park (Illinois) | 1,234.58 mi (1,986.86 km) |
