| Rio Grande City to Laurinburg (North Carolina) | 1,285.05 mi (2,068.09 km) |
| Rio Grande City to Lawndale (California) | 1,274.34 mi (2,050.86 km) |
| Rio Grande City to Lawrence (Indiana) | 1,188.73 mi (1,913.07 km) |
| Rio Grande City to Lawrence (Kansas) | 893.19 mi (1,437.45 km) |
| Rio Grande City to Lawrence (Massachusetts) | 1,921.69 mi (3,092.66 km) |
| Rio Grande City to Lawrenceburg (Kentucky) | 1,142.08 mi (1,838.00 km) |
| Rio Grande City to Lawrenceburg (Tennessee) | 915.39 mi (1,473.18 km) |
| Rio Grande City to Lawrenceville (Georgia) | 1,027.07 mi (1,652.91 km) |
| Rio Grande City to Lawton (Oklahoma) | 569.60 mi (916.68 km) |
| Rio Grande City to Layton (Utah) | 1,262.19 mi (2,031.29 km) |
| Rio Grande City to Le Mars (Iowa) | 1,142.95 mi (1,839.40 km) |
| Rio Grande City to League City (Texas) | 312.11 mi (502.29 km) |
| Rio Grande City to Lealman (Florida) | 996.77 mi (1,604.15 km) |
| Rio Grande City to Leander (Texas) | 295.44 mi (475.47 km) |
| Rio Grande City to Leavenworth (Kansas) | 922.18 mi (1,484.11 km) |
