| Rio Grande City to Laredo (Texas) | 91.37 mi (147.04 km) |
| Rio Grande City to Largo (Florida) | 991.73 mi (1,596.03 km) |
| Rio Grande City to Largo (Maryland) | 1,537.21 mi (2,473.91 km) |
| Rio Grande City to Larkspur (California) | 1,593.39 mi (2,564.31 km) |
| Rio Grande City to Las Cruces (New Mexico) | 631.28 mi (1,015.95 km) |
| Rio Grande City to Las Vegas (Nevada) | 1,182.82 mi (1,903.56 km) |
| Rio Grande City to Las Vegas (New Mexico) | 740.82 mi (1,192.24 km) |
| Rio Grande City to Latham (New York) | 1,807.99 mi (2,909.68 km) |
| Rio Grande City to Lathrop (California) | 1,528.98 mi (2,460.66 km) |
| Rio Grande City to Lauderdale Lakes (Florida) | 1,152.68 mi (1,855.05 km) |
| Rio Grande City to Lauderhill (Florida) | 1,151.34 mi (1,852.90 km) |
| Rio Grande City to Laurel (Florida) | 1,010.44 mi (1,626.15 km) |
| Rio Grande City to Laurel (Maryland) | 1,542.57 mi (2,482.53 km) |
| Rio Grande City to Laurel (Mississippi) | 689.84 mi (1,110.19 km) |
| Rio Grande City to Laurel (Virginia) | 1,465.76 mi (2,358.92 km) |
