| Rio Grande City to Friendly (Maryland) | 1,526.92 mi (2,457.34 km) |
| Rio Grande City to Friendswood (Texas) | 309.29 mi (497.75 km) |
| Rio Grande City to Frisco (Texas) | 483.21 mi (777.65 km) |
| Rio Grande City to Front Royal (Virginia) | 1,474.85 mi (2,373.54 km) |
| Rio Grande City to Fruit Cove (Florida) | 1,077.03 mi (1,733.32 km) |
| Rio Grande City to Fruita (Colorado) | 1,052.18 mi (1,693.32 km) |
| Rio Grande City to Fruitville (Florida) | 1,009.86 mi (1,625.21 km) |
| Rio Grande City to Fuller Heights (Florida) | 1,038.95 mi (1,672.03 km) |
| Rio Grande City to Fullerton (California) | 1,251.20 mi (2,013.61 km) |
| Rio Grande City to Fullerton (Pennsylvania) | 1,657.67 mi (2,667.76 km) |
| Rio Grande City to Fulshear (Texas) | 290.73 mi (467.89 km) |
| Rio Grande City to Fulton (Missouri) | 949.35 mi (1,527.82 km) |
| Rio Grande City to Fulton (New York) | 1,716.81 mi (2,762.94 km) |
| Rio Grande City to Fuquay-Varina (North Carolina) | 1,343.38 mi (2,161.95 km) |
| Rio Grande City to Gadsden (Alabama) | 927.49 mi (1,492.65 km) |
