| Rio Grande City to Eugene (Oregon) | 1,823.55 mi (2,934.71 km) |
| Rio Grande City to Euless (Texas) | 459.08 mi (738.82 km) |
| Rio Grande City to Eureka (California) | 1,755.34 mi (2,824.95 km) |
| Rio Grande City to Eureka (Missouri) | 962.45 mi (1,548.92 km) |
| Rio Grande City to Eustis (Florida) | 1,062.45 mi (1,709.85 km) |
| Rio Grande City to Evans (Colorado) | 1,024.17 mi (1,648.24 km) |
| Rio Grande City to Evans (Georgia) | 1,113.23 mi (1,791.58 km) |
| Rio Grande City to Evanston (Illinois) | 1,252.73 mi (2,016.07 km) |
| Rio Grande City to Evanston (Wyoming) | 1,239.27 mi (1,994.41 km) |
| Rio Grande City to Evansville (Indiana) | 1,036.91 mi (1,668.74 km) |
| Rio Grande City to Everett (Massachusetts) | 1,917.51 mi (3,085.93 km) |
| Rio Grande City to Everett (Washington) | 1,952.33 mi (3,141.97 km) |
| Rio Grande City to Evergreen Park (Illinois) | 1,233.91 mi (1,985.78 km) |
| Rio Grande City to Ewa Beach (Hawaii) | 3,724.87 mi (5,994.60 km) |
| Rio Grande City to Ewa Gentry (Hawaii) | 3,725.68 mi (5,995.91 km) |
