| Rio Grande City to Elkhart (Indiana) | 1,285.60 mi (2,068.98 km) |
| Rio Grande City to Elkhorn (Wisconsin) | 1,266.36 mi (2,038.01 km) |
| Rio Grande City to Elko (Nevada) | 1,390.97 mi (2,238.54 km) |
| Rio Grande City to Elkridge (Maryland) | 1,551.45 mi (2,496.82 km) |
| Rio Grande City to Elkton (Maryland) | 1,608.29 mi (2,588.28 km) |
| Rio Grande City to Ellensburg (Washington) | 1,852.09 mi (2,980.65 km) |
| Rio Grande City to Ellicott City (Maryland) | 1,549.86 mi (2,494.26 km) |
| Rio Grande City to Elmhurst (Illinois) | 1,237.07 mi (1,990.88 km) |
| Rio Grande City to Elmira (New York) | 1,652.12 mi (2,658.83 km) |
| Rio Grande City to Elmont (New York) | 1,742.18 mi (2,803.76 km) |
| Rio Grande City to Elmwood Park (Illinois) | 1,242.13 mi (1,999.01 km) |
| Rio Grande City to Elmwood Park (New Jersey) | 1,729.40 mi (2,783.20 km) |
| Rio Grande City to Elon (North Carolina) | 1,320.16 mi (2,124.59 km) |
| Rio Grande City to Eloy (Arizona) | 883.95 mi (1,422.59 km) |
| Rio Grande City to Elwood (New York) | 1,763.86 mi (2,838.65 km) |
