| Rio Grande City to El Segundo (California) | 1,277.62 mi (2,056.14 km) |
| Rio Grande City to El Sobrante (California) | 1,225.78 mi (1,972.71 km) |
| Rio Grande City to Eldersburg (Maryland) | 1,548.52 mi (2,492.10 km) |
| Rio Grande City to Elfers (Florida) | 995.76 mi (1,602.51 km) |
| Rio Grande City to Elgin (Illinois) | 1,234.69 mi (1,987.03 km) |
| Rio Grande City to Elizabeth (New Jersey) | 1,718.45 mi (2,765.57 km) |
| Rio Grande City to Elizabeth City (North Carolina) | 1,493.31 mi (2,403.26 km) |
| Rio Grande City to Elizabethton (Tennessee) | 1,193.19 mi (1,920.26 km) |
| Rio Grande City to Elizabethtown (Kentucky) | 1,087.17 mi (1,749.64 km) |
| Rio Grande City to Elizabethtown (Pennsylvania) | 1,590.32 mi (2,559.38 km) |
| Rio Grande City to Elk City (Oklahoma) | 623.25 mi (1,003.03 km) |
| Rio Grande City to Elk Grove (California) | 1,550.30 mi (2,494.97 km) |
| Rio Grande City to Elk Grove Village (Illinois) | 1,242.01 mi (1,998.82 km) |
| Rio Grande City to Elk Plain (Washington) | 1,918.46 mi (3,087.46 km) |
| Rio Grande City to Elk River (Minnesota) | 1,341.25 mi (2,158.53 km) |
