| Rio Grande City to East Providence (Rhode Island) | 1,885.42 mi (3,034.29 km) |
| Rio Grande City to East Rancho Dominguez (California) | 1,265.94 mi (2,037.34 km) |
| Rio Grande City to East Renton Highlands (Washington) | 1,927.62 mi (3,102.21 km) |
| Rio Grande City to East Ridge (Tennessee) | 1,001.70 mi (1,612.08 km) |
| Rio Grande City to East Riverdale (Maryland) | 1,535.89 mi (2,471.77 km) |
| Rio Grande City to East San Gabriel (California) | 1,264.72 mi (2,035.38 km) |
| Rio Grande City to East St. Louis (Illinois) | 984.27 mi (1,584.03 km) |
| Rio Grande City to East Wenatchee (Washington) | 1,862.75 mi (2,997.81 km) |
| Rio Grande City to Eastern Goleta Valley (California) | 1,364.35 mi (2,195.70 km) |
| Rio Grande City to Eastlake (Ohio) | 1,445.53 mi (2,326.35 km) |
| Rio Grande City to Eastmont (Washington) | 1,950.30 mi (3,138.71 km) |
| Rio Grande City to Easton (Maryland) | 1,570.37 mi (2,527.26 km) |
| Rio Grande City to Easton (Pennsylvania) | 1,671.54 mi (2,690.08 km) |
| Rio Grande City to Eastpointe (Michigan) | 1,427.96 mi (2,298.09 km) |
| Rio Grande City to Eastvale (California) | 1,234.25 mi (1,986.33 km) |
