| Rio Grande City to East Lake (Florida) | 997.58 mi (1,605.45 km) |
| Rio Grande City to East Lake-Orient Park (Florida) | 1,016.74 mi (1,636.28 km) |
| Rio Grande City to East Lansing (Michigan) | 1,390.04 mi (2,237.06 km) |
| Rio Grande City to East Los Angeles (California) | 1,267.65 mi (2,040.08 km) |
| Rio Grande City to East Massapequa (New York) | 1,754.01 mi (2,822.81 km) |
| Rio Grande City to East Meadow (New York) | 1,749.58 mi (2,815.68 km) |
| Rio Grande City to East Milton (Florida) | 776.69 mi (1,249.97 km) |
| Rio Grande City to East Moline (Illinois) | 1,150.84 mi (1,852.10 km) |
| Rio Grande City to East Niles (California) | 1,340.39 mi (2,157.14 km) |
| Rio Grande City to East Northport (New York) | 1,765.60 mi (2,841.46 km) |
| Rio Grande City to East Orange (New Jersey) | 1,720.67 mi (2,769.15 km) |
| Rio Grande City to East Palo Alto (California) | 1,560.76 mi (2,511.80 km) |
| Rio Grande City to East Patchogue (New York) | 1,778.29 mi (2,861.88 km) |
| Rio Grande City to East Peoria (Illinois) | 1,121.28 mi (1,804.52 km) |
| Rio Grande City to East Point (Georgia) | 993.84 mi (1,599.43 km) |
