| Rio Grande City to Eagan (Minnesota) | 1,312.02 mi (2,111.49 km) |
| Rio Grande City to Eagle (Idaho) | 1,549.64 mi (2,493.90 km) |
| Rio Grande City to Eagle Mountain (Utah) | 1,224.31 mi (1,970.33 km) |
| Rio Grande City to Eagle Pass (Texas) | 190.59 mi (306.72 km) |
| Rio Grande City to Easley (South Carolina) | 1,125.82 mi (1,811.84 km) |
| Rio Grande City to East Bakersfield (California) | 1,343.48 mi (2,162.12 km) |
| Rio Grande City to East Bethel (Minnesota) | 1,347.37 mi (2,168.37 km) |
| Rio Grande City to East Chicago (Indiana) | 1,236.93 mi (1,990.64 km) |
| Rio Grande City to East Cleveland (Ohio) | 1,434.04 mi (2,307.87 km) |
| Rio Grande City to East Glenville (New York) | 1,804.65 mi (2,904.31 km) |
| Rio Grande City to East Grand Rapids (Michigan) | 1,365.08 mi (2,196.88 km) |
| Rio Grande City to East Hemet (California) | 1,194.29 mi (1,922.03 km) |
| Rio Grande City to East Highland Park (Virginia) | 1,469.86 mi (2,365.50 km) |
| Rio Grande City to East Honolulu (Hawaii) | 3,707.76 mi (5,967.06 km) |
| Rio Grande City to East Islip (New York) | 1,767.28 mi (2,844.17 km) |
