| Rio Grande City to Dixon (California) | 1,572.76 mi (2,531.11 km) |
| Rio Grande City to Dixon (Illinois) | 1,192.78 mi (1,919.60 km) |
| Rio Grande City to Dobbs Ferry (New York) | 1,744.43 mi (2,807.39 km) |
| Rio Grande City to Doctor Phillips (Florida) | 1,071.52 mi (1,724.44 km) |
| Rio Grande City to Dodge City (Kansas) | 789.40 mi (1,270.41 km) |
| Rio Grande City to Dolton (Illinois) | 1,231.64 mi (1,982.14 km) |
| Rio Grande City to Donna (Texas) | 50.12 mi (80.65 km) |
| Rio Grande City to Dorado (Puerto Rico) | 2,143.12 mi (3,449.02 km) |
| Rio Grande City to Doral (Florida) | 1,145.42 mi (1,843.38 km) |
| Rio Grande City to Doraville (Georgia) | 1,011.45 mi (1,627.77 km) |
| Rio Grande City to Dothan (Alabama) | 877.81 mi (1,412.70 km) |
| Rio Grande City to Douglas (Arizona) | 733.57 mi (1,180.56 km) |
| Rio Grande City to Douglas (Georgia) | 1,027.06 mi (1,652.89 km) |
| Rio Grande City to Douglasville (Georgia) | 983.94 mi (1,583.51 km) |
| Rio Grande City to Dover (Delaware) | 1,608.63 mi (2,588.85 km) |
