| Rio Grande City to Darby (Pennsylvania) | 1,644.70 mi (2,646.89 km) |
| Rio Grande City to Dardenne Prairie (Missouri) | 975.20 mi (1,569.43 km) |
| Rio Grande City to Darien (Illinois) | 1,227.18 mi (1,974.95 km) |
| Rio Grande City to Davenport (Iowa) | 1,148.00 mi (1,847.52 km) |
| Rio Grande City to Davidson (North Carolina) | 1,235.22 mi (1,987.90 km) |
| Rio Grande City to Davie (Florida) | 1,147.94 mi (1,847.44 km) |
| Rio Grande City to Davis (California) | 1,571.67 mi (2,529.35 km) |
| Rio Grande City to Dayton (Nevada) | 1,491.32 mi (2,400.05 km) |
| Rio Grande City to Dayton (Ohio) | 1,251.02 mi (2,013.33 km) |
| Rio Grande City to Daytona Beach (Florida) | 1,099.56 mi (1,769.57 km) |
| Rio Grande City to De Pere (Wisconsin) | 1,383.24 mi (2,226.11 km) |
| Rio Grande City to De Witt (New York) | 1,719.20 mi (2,766.78 km) |
| Rio Grande City to Dearborn (Michigan) | 1,410.91 mi (2,270.63 km) |
| Rio Grande City to Dearborn Heights (Michigan) | 1,408.84 mi (2,267.31 km) |
| Rio Grande City to DeBary (Florida) | 1,083.88 mi (1,744.34 km) |
