| Rio Grande City to Crawfordsville (Indiana) | 1,166.40 mi (1,877.13 km) |
| Rio Grande City to Crest Hill (Illinois) | 1,213.53 mi (1,952.98 km) |
| Rio Grande City to Crestview (Florida) | 801.26 mi (1,289.51 km) |
| Rio Grande City to Crestwood (Illinois) | 1,228.46 mi (1,977.01 km) |
| Rio Grande City to Crestwood (Missouri) | 973.58 mi (1,566.82 km) |
| Rio Grande City to Creve Coeur (Missouri) | 977.83 mi (1,573.66 km) |
| Rio Grande City to Crofton (Maryland) | 1,548.61 mi (2,492.25 km) |
| Rio Grande City to Crossville (Tennessee) | 1,047.92 mi (1,686.46 km) |
| Rio Grande City to Crowley (Louisiana) | 473.20 mi (761.55 km) |
| Rio Grande City to Crowley (Texas) | 437.12 mi (703.48 km) |
| Rio Grande City to Crown Point (Indiana) | 1,227.09 mi (1,974.81 km) |
| Rio Grande City to Crystal (Minnesota) | 1,324.17 mi (2,131.05 km) |
| Rio Grande City to Crystal Lake (Illinois) | 1,245.82 mi (2,004.95 km) |
| Rio Grande City to Cudahy (California) | 1,266.81 mi (2,038.73 km) |
| Rio Grande City to Cudahy (Wisconsin) | 1,300.33 mi (2,092.68 km) |
