| Rio Grande City to Conyers (Georgia) | 1,018.13 mi (1,638.51 km) |
| Rio Grande City to Cookeville (Tennessee) | 1,034.17 mi (1,664.34 km) |
| Rio Grande City to Coolidge (Arizona) | 886.07 mi (1,425.99 km) |
| Rio Grande City to Coon Rapids (Minnesota) | 1,334.00 mi (2,146.87 km) |
| Rio Grande City to Cooper City (Florida) | 1,148.20 mi (1,847.85 km) |
| Rio Grande City to Coos Bay (Oregon) | 1,845.27 mi (2,969.68 km) |
| Rio Grande City to Copiague (New York) | 1,755.96 mi (2,825.94 km) |
| Rio Grande City to Coppell (Texas) | 467.92 mi (753.04 km) |
| Rio Grande City to Copperas Cove (Texas) | 331.97 mi (534.25 km) |
| Rio Grande City to Coral Gables (Florida) | 1,151.51 mi (1,853.18 km) |
| Rio Grande City to Coral Springs (Florida) | 1,148.55 mi (1,848.42 km) |
| Rio Grande City to Coral Terrace (Florida) | 1,149.12 mi (1,849.33 km) |
| Rio Grande City to Coralville (Iowa) | 1,135.25 mi (1,827.01 km) |
| Rio Grande City to Coram (New York) | 1,780.52 mi (2,865.47 km) |
| Rio Grande City to Corcoran (California) | 1,392.42 mi (2,240.88 km) |
