| Rio Grande City to Cold Springs (Nevada) | 1,525.47 mi (2,455.01 km) |
| Rio Grande City to Coldwater (Michigan) | 1,330.79 mi (2,141.70 km) |
| Rio Grande City to Colesville (Maryland) | 1,535.30 mi (2,470.83 km) |
| Rio Grande City to College (Alaska) | 3,407.46 mi (5,483.77 km) |
| Rio Grande City to College Park (Georgia) | 993.12 mi (1,598.28 km) |
| Rio Grande City to College Park (Maryland) | 1,535.97 mi (2,471.91 km) |
| Rio Grande City to College Station (Texas) | 328.47 mi (528.62 km) |
| Rio Grande City to Collegedale (Tennessee) | 1,012.32 mi (1,629.17 km) |
| Rio Grande City to Colleyville (Texas) | 460.89 mi (741.73 km) |
| Rio Grande City to Collierville (Tennessee) | 806.77 mi (1,298.37 km) |
| Rio Grande City to Collinsville (Illinois) | 991.51 mi (1,595.68 km) |
| Rio Grande City to Colonia (New Jersey) | 1,710.37 mi (2,752.57 km) |
| Rio Grande City to Colonial Heights (Virginia) | 1,460.17 mi (2,349.91 km) |
| Rio Grande City to Colonial Park (Pennsylvania) | 1,585.91 mi (2,552.28 km) |
| Rio Grande City to Colorado Springs (Colorado) | 928.80 mi (1,494.76 km) |
