| Rio Grande City to Cloverleaf (Texas) | 323.85 mi (521.18 km) |
| Rio Grande City to Cloverly (Maryland) | 1,536.47 mi (2,472.70 km) |
| Rio Grande City to Clovis (California) | 1,419.33 mi (2,284.19 km) |
| Rio Grande City to Clovis (New Mexico) | 614.39 mi (988.77 km) |
| Rio Grande City to Clute (Texas) | 277.94 mi (447.29 km) |
| Rio Grande City to Coachella (California) | 1,150.46 mi (1,851.49 km) |
| Rio Grande City to Coalinga (California) | 1,433.29 mi (2,306.66 km) |
| Rio Grande City to Coamo (Puerto Rico) | 2,147.19 mi (3,455.56 km) |
| Rio Grande City to Coatesville (Pennsylvania) | 1,620.61 mi (2,608.12 km) |
| Rio Grande City to Cockeysville (Maryland) | 1,566.18 mi (2,520.53 km) |
| Rio Grande City to Cocoa (Florida) | 1,115.18 mi (1,794.71 km) |
| Rio Grande City to Cocoa Beach (Florida) | 1,123.53 mi (1,808.14 km) |
| Rio Grande City to Coconut Creek (Florida) | 1,153.12 mi (1,855.77 km) |
| Rio Grande City to Coeur d'Alene (Idaho) | 1,766.08 mi (2,842.23 km) |
| Rio Grande City to Cohoes (New York) | 1,810.89 mi (2,914.35 km) |
