| Rio Grande City to Clarksdale (Mississippi) | 730.01 mi (1,174.84 km) |
| Rio Grande City to Clarkston (Georgia) | 1,010.04 mi (1,625.51 km) |
| Rio Grande City to Clarksville (Indiana) | 1,120.68 mi (1,803.57 km) |
| Rio Grande City to Clarksville (Tennessee) | 974.79 mi (1,568.77 km) |
| Rio Grande City to Clawson (Michigan) | 1,424.32 mi (2,292.23 km) |
| Rio Grande City to Clay (Alabama) | 887.15 mi (1,427.72 km) |
| Rio Grande City to Clayton (California) | 1,563.39 mi (2,516.04 km) |
| Rio Grande City to Clayton (Missouri) | 980.07 mi (1,577.26 km) |
| Rio Grande City to Clayton (North Carolina) | 1,362.08 mi (2,192.05 km) |
| Rio Grande City to Clayton (Ohio) | 1,250.28 mi (2,012.12 km) |
| Rio Grande City to Clearfield (Utah) | 1,265.64 mi (2,036.86 km) |
| Rio Grande City to Clearlake (California) | 1,627.23 mi (2,618.78 km) |
| Rio Grande City to Clearwater (Florida) | 992.49 mi (1,597.25 km) |
| Rio Grande City to Cleburne (Texas) | 421.48 mi (678.31 km) |
| Rio Grande City to Clemmons (North Carolina) | 1,273.93 mi (2,050.19 km) |
