| Rio Grande City to Cibolo (Texas) | 223.02 mi (358.92 km) |
| Rio Grande City to Cicero (Illinois) | 1,239.28 mi (1,994.43 km) |
| Rio Grande City to Cimarron Hills (Colorado) | 927.01 mi (1,491.88 km) |
| Rio Grande City to Cincinnati (Ohio) | 1,209.00 mi (1,945.70 km) |
| Rio Grande City to Cinco Ranch (Texas) | 297.76 mi (479.20 km) |
| Rio Grande City to Circleville (Ohio) | 1,293.28 mi (2,081.34 km) |
| Rio Grande City to Citrus (California) | 1,254.51 mi (2,018.95 km) |
| Rio Grande City to Citrus Heights (California) | 1,554.12 mi (2,501.12 km) |
| Rio Grande City to Citrus Park (Florida) | 1,004.95 mi (1,617.32 km) |
| Rio Grande City to Claiborne (Louisiana) | 582.59 mi (937.58 km) |
| Rio Grande City to Claremont (California) | 1,245.42 mi (2,004.31 km) |
| Rio Grande City to Claremont (New Hampshire) | 1,891.74 mi (3,044.47 km) |
| Rio Grande City to Claremore (Oklahoma) | 711.91 mi (1,145.71 km) |
| Rio Grande City to Clarksburg (Maryland) | 1,527.87 mi (2,458.87 km) |
| Rio Grande City to Clarksburg (West Virginia) | 1,390.84 mi (2,238.34 km) |
