| Rio Grande City to Castle Pines (Colorado) | 968.92 mi (1,559.32 km) |
| Rio Grande City to Castle Rock (Colorado) | 963.08 mi (1,549.92 km) |
| Rio Grande City to Castro Valley (California) | 1,563.61 mi (2,516.39 km) |
| Rio Grande City to Catalina Foothills (Arizona) | 833.03 mi (1,340.63 km) |
| Rio Grande City to Cataño (Puerto Rico) | 2,151.69 mi (3,462.82 km) |
| Rio Grande City to Cathedral City (California) | 1,171.32 mi (1,885.05 km) |
| Rio Grande City to Catonsville (Maryland) | 1,553.77 mi (2,500.56 km) |
| Rio Grande City to Cave Spring (Virginia) | 1,330.80 mi (2,141.71 km) |
| Rio Grande City to Cayce (South Carolina) | 1,181.34 mi (1,901.18 km) |
| Rio Grande City to Cayey (Puerto Rico) | 2,158.51 mi (3,473.78 km) |
| Rio Grande City to Cedar City (Utah) | 1,141.46 mi (1,837.01 km) |
| Rio Grande City to Cedar Falls (Iowa) | 1,171.70 mi (1,885.67 km) |
| Rio Grande City to Cedar Hill (Texas) | 442.77 mi (712.57 km) |
| Rio Grande City to Cedar Lake (Indiana) | 1,221.76 mi (1,966.23 km) |
| Rio Grande City to Cedar Mill (Oregon) | 1,870.13 mi (3,009.68 km) |
