| Rio Grande City to Cadillac (Michigan) | 1,443.21 mi (2,322.63 km) |
| Rio Grande City to Caguas (Puerto Rico) | 2,163.20 mi (3,481.34 km) |
| Rio Grande City to Cahokia (Illinois) | 979.90 mi (1,577.00 km) |
| Rio Grande City to Calabasas (California) | 1,297.04 mi (2,087.38 km) |
| Rio Grande City to Caldwell (Idaho) | 1,555.62 mi (2,503.53 km) |
| Rio Grande City to Caledonia (Wisconsin) | 1,291.32 mi (2,078.19 km) |
| Rio Grande City to Calera (Alabama) | 860.38 mi (1,384.65 km) |
| Rio Grande City to Calexico (California) | 1,091.16 mi (1,756.05 km) |
| Rio Grande City to Calhoun (Georgia) | 997.39 mi (1,605.15 km) |
| Rio Grande City to California (Maryland) | 1,535.20 mi (2,470.67 km) |
| Rio Grande City to California City (California) | 1,280.08 mi (2,060.09 km) |
| Rio Grande City to Callaway (Florida) | 847.28 mi (1,363.57 km) |
| Rio Grande City to Calumet City (Illinois) | 1,232.19 mi (1,983.02 km) |
| Rio Grande City to Calverton (Maryland) | 1,537.27 mi (2,474.00 km) |
| Rio Grande City to Camano (Washington) | 1,973.54 mi (3,176.11 km) |
