| Rio Grande City to Phoenix (Arizona) | 935.46 mi (1,505.48 km) |
| Rio Grande City to St. Louis (Missouri) | 982.06 mi (1,580.48 km) |
| Rio Grande City to Denver (Colorado) | 988.11 mi (1,590.21 km) |
| Rio Grande City to Atlanta (Georgia) | 999.21 mi (1,608.07 km) |
| Rio Grande City to Tampa (Florida) | 1,011.89 mi (1,628.48 km) |
| Rio Grande City to Miami (Florida) | 1,154.71 mi (1,858.32 km) |
| Rio Grande City to Las Vegas (Nevada) | 1,182.82 mi (1,903.56 km) |
| Rio Grande City to San Diego (California) | 1,184.15 mi (1,905.70 km) |
| Rio Grande City to Riverside (California) | 1,223.71 mi (1,969.37 km) |
| Rio Grande City to Chicago (Illinois) | 1,240.97 mi (1,997.15 km) |
| Rio Grande City to Los Angeles (California) | 1,282.35 mi (2,063.74 km) |
| Rio Grande City to Minneapolis (Minnesota) | 1,320.40 mi (2,124.98 km) |
| Rio Grande City to Detroit (Michigan) | 1,418.34 mi (2,282.60 km) |
| Rio Grande City to Washington (District of Columbia) | 1,529.09 mi (2,460.84 km) |
| Rio Grande City to Baltimore (Maryland) | 1,561.13 mi (2,512.39 km) |
| Rio Grande City to San Francisco (California) | 1,584.10 mi (2,549.37 km) |
| Rio Grande City to Philadelphia (Pennsylvania) | 1,653.43 mi (2,660.94 km) |
| Rio Grande City to Brooklyn (New York) | 1,729.21 mi (2,782.90 km) |
| Rio Grande City to New York (New York) | 1,731.76 mi (2,786.99 km) |
| Rio Grande City to Queens (New York) | 1,739.44 mi (2,799.35 km) |
| Rio Grande City to Portland (Oregon) | 1,864.37 mi (3,000.42 km) |
| Rio Grande City to Boston (Massachusetts) | 1,913.42 mi (3,079.35 km) |
| Rio Grande City to Seattle (Washington) | 1,942.80 mi (3,126.63 km) |
| Rio Grande City to Houston (Texas) | 314.84 mi (506.68 km) |
| Rio Grande City to Dallas (Texas) | 459.92 mi (740.17 km) |
