| Reston to Storm Lake (Iowa) | 965.84 mi (1,554.36 km) |
| Reston to Storrs (Connecticut) | 332.94 mi (535.81 km) |
| Reston to Stoughton (Wisconsin) | 677.18 mi (1,089.81 km) |
| Reston to Stow (Ohio) | 265.30 mi (426.95 km) |
| Reston to Streamwood (Illinois) | 606.94 mi (976.78 km) |
| Reston to Streator (Illinois) | 625.27 mi (1,006.27 km) |
| Reston to Streetsboro (Ohio) | 264.00 mi (424.86 km) |
| Reston to Strongsville (Ohio) | 287.68 mi (462.98 km) |
| Reston to Stuart (Florida) | 829.13 mi (1,334.35 km) |
| Reston to Stuarts Draft (Virginia) | 111.73 mi (179.81 km) |
| Reston to Sturgis (Michigan) | 468.04 mi (753.23 km) |
| Reston to Suamico (Wisconsin) | 676.87 mi (1,089.32 km) |
| Reston to Sudley (Virginia) | 13.79 mi (22.20 km) |
| Reston to Suffern (New York) | 226.00 mi (363.70 km) |
| Reston to Suffolk (Virginia) | 160.46 mi (258.24 km) |
